Bigger the client, better. However, it depends on your business model, city in which you work, your social circle and your past experience. Everyone wishes to have big clients. However, all big clients were small one day. You need to nurture a client over years and only then you can reap the rewards. If you start with small clients, you should be prepared that it will take time for your business to grow big. If the client has potential to grow, you should take him on board.
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